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Synthesis of Fluorescent Probes based on Stilbenes and Diphenylacetylenes targeting β-Amyloid Plaques
Three fluorescent probes were synthesized aiming for optical imaging to detect amyloid plaques present in patients with Alzheimer’s disease (AD). These compounds were prepared via Sonogashira coupling of a well-defined fluorophore (4-bora-3a, 4a-diaza s-indacene, BODIPY) with the pharmacophore posse...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2008
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2504756/ https://ncbi.nlm.nih.gov/pubmed/19122762 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2008.03.130 |
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