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Synthesis of Fluorescent Probes based on Stilbenes and Diphenylacetylenes targeting β-Amyloid Plaques

Three fluorescent probes were synthesized aiming for optical imaging to detect amyloid plaques present in patients with Alzheimer’s disease (AD). These compounds were prepared via Sonogashira coupling of a well-defined fluorophore (4-bora-3a, 4a-diaza s-indacene, BODIPY) with the pharmacophore posse...

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Detalhes bibliográficos
Main Authors: Parhi, Ajit K., Kung, Mei-Ping, Ploessl, Karl, Kung, Hank F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2504756/
https://ncbi.nlm.nih.gov/pubmed/19122762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2008.03.130
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