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Quick Assembly of 1,4-Diphenyltriazoles as Probes Targeting β-Amyloid Aggregates in Alzheimer’s Disease

Accumulation of β-amyloid aggregates (Aβ) in the brain is linked to the pathogenesis of Alzheimer’s disease (AD). We report a novel approach for producing 1,4-diphenyltriazoles as probes for targeting Aβ aggregates in the brain. The imaging probes, a series of substituted tricyclic 1,4-diphenyltriaz...

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Bibliographic Details
Main Authors: Qu, Wenchao, Kung, Mei-Ping, Hou, Catherine, Oya, Shunichi, Kung, Hank F.
Format: Artigo
Language:Inglês
Published: 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3374157/
https://ncbi.nlm.nih.gov/pubmed/17569520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm070467l
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