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Radioiodinated aza-diphenylacetylenes as potential SPECT imaging agents for β-amyloid plaque detection
Two new iodinated fluoro- and hydroxy-pegylated aza-diphenylacetylene derivatives, 1 and 2, targeting β-amyloid (Aβ) plaques have been successfully prepared. In vitro binding carried out in tissue homogenates prepared from postmortem AD brains with [(125)I]IMPY (6-iodo-2-(4′-dimethylamino-)phenyl-im...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1950143/ https://ncbi.nlm.nih.gov/pubmed/17502139 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2007.04.062 |
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