DNA methylation analysis by digital bisulfite genomic sequencing and digital MethyLight

Alterations in cytosine-5 DNA methylation are frequently observed in most types of human cancer. Although assays utilizing PCR amplification of bisulfite-converted DNA are widely employed to analyze these DNA methylation alterations, they are generally limited in throughput capacity, detection sensi...

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Hlavní autoři: Weisenberger, Daniel J., Trinh, Binh N., Campan, Mihaela, Sharma, Shikhar, Long, Tiffany I., Ananthnarayan, Suchitra, Liang, Gangning, Esteva, Francisco J., Hortobagyi, Gabriel N., McCormick, Frank, Jones, Peter A., Laird, Peter W.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2008
Témata:
Molecular Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2504308/
https://ncbi.nlm.nih.gov/pubmed/18628296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn455
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