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MethyLight droplet digital PCR for detection and absolute quantification of infrequently methylated alleles

Aberrant DNA methylation is a common epigenetic alteration found in colorectal adenomas and cancers and plays a role in cancer initiation and progression. Aberrantly methylated DNA loci can also be found infrequently present in normal colon tissue, where they seem to have potential to be used as col...

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Detalhes bibliográficos
Publicado no:Epigenetics
Main Authors: Yu, Ming, Carter, Kelly T, Makar, Karen W, Vickers, Kathy, Ulrich, Cornelia M, Schoen, Robert E, Brenner, Dean, Markowitz, Sanford D, Grady, William M
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4623055/
https://ncbi.nlm.nih.gov/pubmed/26186366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2015.1068490
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