MethyLight droplet digital PCR for detection and absolute quantification of infrequently methylated alleles

Aberrant DNA methylation is a common epigenetic alteration found in colorectal adenomas and cancers and plays a role in cancer initiation and progression. Aberrantly methylated DNA loci can also be found infrequently present in normal colon tissue, where they seem to have potential to be used as col...

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Publicat a:Epigenetics
Autors principals: Yu, Ming, Carter, Kelly T, Makar, Karen W, Vickers, Kathy, Ulrich, Cornelia M, Schoen, Robert E, Brenner, Dean, Markowitz, Sanford D, Grady, William M
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2015
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4623055/
https://ncbi.nlm.nih.gov/pubmed/26186366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2015.1068490
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