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MethyLight: a high-throughput assay to measure DNA methylation

Cytosine-5 DNA methylation occurs in the context of CpG dinucleotides in vertebrates. Aberrant methylation of CpG islands in human tumors has been shown to cause transcriptional silencing of tumor-suppressor genes. Most methods used to analyze cytosine-5 methylation patterns require cumbersome manua...

詳細記述

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書誌詳細
主要な著者: Eads, Cindy A., Danenberg, Kathleen D., Kawakami, Kazuyuki, Saltz, Leonard B., Blake, Corey, Shibata, Darryl, Danenberg, Peter V., Laird, Peter W.
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2000
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC102836/
https://ncbi.nlm.nih.gov/pubmed/10734209
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