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MethyLight: a high-throughput assay to measure DNA methylation

Cytosine-5 DNA methylation occurs in the context of CpG dinucleotides in vertebrates. Aberrant methylation of CpG islands in human tumors has been shown to cause transcriptional silencing of tumor-suppressor genes. Most methods used to analyze cytosine-5 methylation patterns require cumbersome manua...

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Bibliografische gegevens
Hoofdauteurs: Eads, Cindy A., Danenberg, Kathleen D., Kawakami, Kazuyuki, Saltz, Leonard B., Blake, Corey, Shibata, Darryl, Danenberg, Peter V., Laird, Peter W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2000
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC102836/
https://ncbi.nlm.nih.gov/pubmed/10734209
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