DNA methylation analysis by digital bisulfite genomic sequencing and digital MethyLight

Alterations in cytosine-5 DNA methylation are frequently observed in most types of human cancer. Although assays utilizing PCR amplification of bisulfite-converted DNA are widely employed to analyze these DNA methylation alterations, they are generally limited in throughput capacity, detection sensi...

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Main Authors: Weisenberger, Daniel J., Trinh, Binh N., Campan, Mihaela, Sharma, Shikhar, Long, Tiffany I., Ananthnarayan, Suchitra, Liang, Gangning, Esteva, Francisco J., Hortobagyi, Gabriel N., McCormick, Frank, Jones, Peter A., Laird, Peter W.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2008
Ábhair:
Molecular Biology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2504308/
https://ncbi.nlm.nih.gov/pubmed/18628296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn455
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