DNA methylation analysis by digital bisulfite genomic sequencing and digital MethyLight

Alterations in cytosine-5 DNA methylation are frequently observed in most types of human cancer. Although assays utilizing PCR amplification of bisulfite-converted DNA are widely employed to analyze these DNA methylation alterations, they are generally limited in throughput capacity, detection sensi...

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Bibliographische Detailangaben
Hauptverfasser: Weisenberger, Daniel J., Trinh, Binh N., Campan, Mihaela, Sharma, Shikhar, Long, Tiffany I., Ananthnarayan, Suchitra, Liang, Gangning, Esteva, Francisco J., Hortobagyi, Gabriel N., McCormick, Frank, Jones, Peter A., Laird, Peter W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2008
Schlagworte:
Molecular Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2504308/
https://ncbi.nlm.nih.gov/pubmed/18628296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn455
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