Separate molecules of West Nile virus methyltransferase can independently catalyze the N7 and 2′-O methylations of viral RNA cap

West Nile virus methyltransferase catalyzes N7 and 2′-O methylations of the viral RNA cap (GpppA-RNA→m(7)GpppAm-RNA). The two methylation events are independent, as evidenced by efficient N7 methylation of GpppA-RNA→m(7)GpppA-RNA and GpppAm-RNA→m(7)GpppAm-RNA, and by the 2′-O methylation of GpppA-RN...

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Bibliographic Details
Main Authors:	Dong, Hongping, Ren, Suping, Li, Hongmin, Shi, Pei-Yong
Format:	Artigo
Language:	Inglês
Published:	2008
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2494700/ https://ncbi.nlm.nih.gov/pubmed/18501946 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2008.04.026
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Separate molecules of West Nile virus methyltransferase can independently catalyze the N7 and 2′-O methylations of viral RNA cap

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