Lataa...

West Nile Virus Methyltransferase Catalyzes Two Methylations of the Viral RNA Cap through a Substrate-Repositioning Mechanism

Flaviviruses encode a single methyltransferase domain that sequentially catalyzes two methylations of the viral RNA cap, GpppA-RNA→m(7)GpppA-RNA→m(7)GpppAm-RNA, by using S-adenosyl-l-methionine (SAM) as a methyl donor. Crystal structures of flavivirus methyltransferases exhibit distinct binding site...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Dong, Hongping, Ren, Suping, Zhang, Bo, Zhou, Yangsheng, Puig-Basagoiti, Francesc, Li, Hongmin, Shi, Pei-Yong
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology (ASM) 2008
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2293060/
https://ncbi.nlm.nih.gov/pubmed/18305027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02202-07
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!