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Separate molecules of West Nile virus methyltransferase can independently catalyze the N7 and 2′-O methylations of viral RNA cap
West Nile virus methyltransferase catalyzes N7 and 2′-O methylations of the viral RNA cap (GpppA-RNA→m(7)GpppAm-RNA). The two methylation events are independent, as evidenced by efficient N7 methylation of GpppA-RNA→m(7)GpppA-RNA and GpppAm-RNA→m(7)GpppAm-RNA, and by the 2′-O methylation of GpppA-RN...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2494700/ https://ncbi.nlm.nih.gov/pubmed/18501946 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2008.04.026 |
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