Llwytho...

Protein Targets of Reactive Metabolites of Thiobenzamide in Rat Liver In Vivo

Thiobenzamide (TB) is a potent hepatotoxin in rats, causing dose-dependent hyperbilirubinemia, steatosis, and centrolobular necrosis. These effects arise subsequent to and appear to result from the covalent binding of the iminosulfinic acid metabolite of TB to cellular proteins and phosphatidylethan...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ikehata, Keisuke, Duzhak, Tatyana G., Galeva, Nadezhda A., Ji, Tao, Koen, Yakov M., Hanzlik, Robert P.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2493440/
https://ncbi.nlm.nih.gov/pubmed/18547066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx800093k
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