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Liver Protein Targets of Hepatotoxic 4-Bromophenol Metabolites
The hepatotoxicity of bromobenzene (BB) is directly related to the covalent binding of both initially formed epoxide and secondary quinone metabolites to at least 45 different liver proteins. 4-Bromophenol (4BP) is a significant BB metabolite and a precursor to reactive quinone metabolites, yet when...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3431021/ https://ncbi.nlm.nih.gov/pubmed/22827705 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx3002675 |
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