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Detection and characterization of silencers and enhancer-blockers in the greater CFTR locus
Silencers and enhancer-blockers (EBs) are cis-acting, negative regulatory elements (NREs) that control interactions between promoters and enhancers. Although relatively uncharacterized in terms of biological mechanisms, these elements are likely to be abundant in the genome. We developed an experime...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Cold Spring Harbor Laboratory Press
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2493434/ https://ncbi.nlm.nih.gov/pubmed/18436892 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.073817.107 |
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