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Robust Detection of DNA Hypermethylation of ZNF154 as a Pan-Cancer Locus with in Silico Modeling for Blood-Based Diagnostic Development

Sites that display recurrent, aberrant DNA methylation in cancer represent potential biomarkers for screening and diagnostics. Previously, we identified hypermethylation at the ZNF154 CpG island in 15 solid epithelial tumor types from 13 different organs. In this study, we measure the magnitude and...

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Detalles Bibliográficos
Publicado en:J Mol Diagn
Main Authors: Margolin, Gennady, Petrykowska, Hanna M., Jameel, Nader, Bell, Daphne W., Young, Alice C., Elnitski, Laura
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Investigative Pathology 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816708/
https://ncbi.nlm.nih.gov/pubmed/26857064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmoldx.2015.11.004
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