Robust Detection of DNA Hypermethylation of ZNF154 as a Pan-Cancer Locus with in Silico Modeling for Blood-Based Diagnostic Development

Sites that display recurrent, aberrant DNA methylation in cancer represent potential biomarkers for screening and diagnostics. Previously, we identified hypermethylation at the ZNF154 CpG island in 15 solid epithelial tumor types from 13 different organs. In this study, we measure the magnitude and...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Mol Diagn
Egile Nagusiak: Margolin, Gennady, Petrykowska, Hanna M., Jameel, Nader, Bell, Daphne W., Young, Alice C., Elnitski, Laura
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Investigative Pathology 2016
Gaiak:
Regular Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816708/
https://ncbi.nlm.nih.gov/pubmed/26857064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmoldx.2015.11.004
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