Robust Detection of DNA Hypermethylation of ZNF154 as a Pan-Cancer Locus with in Silico Modeling for Blood-Based Diagnostic Development

Sites that display recurrent, aberrant DNA methylation in cancer represent potential biomarkers for screening and diagnostics. Previously, we identified hypermethylation at the ZNF154 CpG island in 15 solid epithelial tumor types from 13 different organs. In this study, we measure the magnitude and...

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Bibliografski detalji
Izdano u:J Mol Diagn
Glavni autori: Margolin, Gennady, Petrykowska, Hanna M., Jameel, Nader, Bell, Daphne W., Young, Alice C., Elnitski, Laura
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2016
Teme:
Regular Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816708/
https://ncbi.nlm.nih.gov/pubmed/26857064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmoldx.2015.11.004
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