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Detection and characterization of silencers and enhancer-blockers in the greater CFTR locus

Silencers and enhancer-blockers (EBs) are cis-acting, negative regulatory elements (NREs) that control interactions between promoters and enhancers. Although relatively uncharacterized in terms of biological mechanisms, these elements are likely to be abundant in the genome. We developed an experime...

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Autori principali: Petrykowska, Hanna M., Vockley, Christopher M., Elnitski, Laura
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2493434/
https://ncbi.nlm.nih.gov/pubmed/18436892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.073817.107
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