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Detection and characterization of silencers and enhancer-blockers in the greater CFTR locus

Silencers and enhancer-blockers (EBs) are cis-acting, negative regulatory elements (NREs) that control interactions between promoters and enhancers. Although relatively uncharacterized in terms of biological mechanisms, these elements are likely to be abundant in the genome. We developed an experime...

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書目詳細資料
Main Authors: Petrykowska, Hanna M., Vockley, Christopher M., Elnitski, Laura
格式: Artigo
語言:Inglês
出版: Cold Spring Harbor Laboratory Press 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2493434/
https://ncbi.nlm.nih.gov/pubmed/18436892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.073817.107
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