Nuclear HuR accumulation through phosphorylation by Cdk1

A predominantly nuclear RNA-binding protein, HuR translocates to the cytoplasm in response to stress and proliferative signals, where it stabilizes or modulates the translation of target mRNAs. Here, we present evidence that HuR phosphorylation at S202 by the G2-phase kinase Cdk1 influences its subc...

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Detaylı Bibliyografya
Asıl Yazarlar: Kim, Hyeon Ho, Abdelmohsen, Kotb, Lal, Ashish, Pullmann, Rudolf, Yang, Xiaoling, Galban, Stefanie, Srikantan, Subramanya, Martindale, Jennifer L., Blethrow, Justin, Shokat, Kevan M., Gorospe, Myriam
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory Press 2008
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2492667/
https://ncbi.nlm.nih.gov/pubmed/18593881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1645808
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