RNA-Binding Proteins HuR and PTB Promote the Translation of Hypoxia-Inducible Factor 1α

The levels of hypoxia-inducible factor 1α (HIF-1α) are tightly controlled. Here, we investigated the posttranscriptional regulation of HIF-1α expression in human cervical carcinoma HeLa cells responding to the hypoxia mimetic CoCl(2). Undetectable in untreated cells, HIF-1α levels increased dramatic...

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Detalhes bibliográficos
Main Authors: Galbán, Stefanie, Kuwano, Yuki, Pullmann, Rudolf, Martindale, Jennifer L., Kim, Hyeon Ho, Lal, Ashish, Abdelmohsen, Kotb, Yang, Xiaoling, Dang, Youngjun, Liu, Jun O., Lewis, Stephen M., Holcik, Martin, Gorospe, Myriam
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2223304/
https://ncbi.nlm.nih.gov/pubmed/17967866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00973-07
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