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RNA-Binding Proteins HuR and PTB Promote the Translation of Hypoxia-Inducible Factor 1α
The levels of hypoxia-inducible factor 1α (HIF-1α) are tightly controlled. Here, we investigated the posttranscriptional regulation of HIF-1α expression in human cervical carcinoma HeLa cells responding to the hypoxia mimetic CoCl(2). Undetectable in untreated cells, HIF-1α levels increased dramatic...
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| 主要な著者: | , , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology (ASM)
2008
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2223304/ https://ncbi.nlm.nih.gov/pubmed/17967866 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00973-07 |
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