Tyrosine phosphorylation of HuR by JAK3 triggers dissociation and degradation of HuR target mRNAs

In response to stress conditions, many mammalian mRNAs accumulate in stress granules (SGs) together with numerous RNA-binding proteins that control mRNA turnover and translation. However, the signaling cascades that modulate the presence of ribonucleoprotein (RNP) complexes in SGs are poorly underst...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Yoon, Je-Hyun, Abdelmohsen, Kotb, Srikantan, Subramanya, Guo, Rong, Yang, Xiaoling, Martindale, Jennifer L., Gorospe, Myriam
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2014
Gaiak:
RNA
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3902907/
https://ncbi.nlm.nih.gov/pubmed/24106086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt903
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