Tyrosine phosphorylation of HuR by JAK3 triggers dissociation and degradation of HuR target mRNAs

In response to stress conditions, many mammalian mRNAs accumulate in stress granules (SGs) together with numerous RNA-binding proteins that control mRNA turnover and translation. However, the signaling cascades that modulate the presence of ribonucleoprotein (RNP) complexes in SGs are poorly underst...

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Bibliografiske detaljer
Main Authors: Yoon, Je-Hyun, Abdelmohsen, Kotb, Srikantan, Subramanya, Guo, Rong, Yang, Xiaoling, Martindale, Jennifer L., Gorospe, Myriam
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
Fag:
RNA
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3902907/
https://ncbi.nlm.nih.gov/pubmed/24106086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt903
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