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Tyrosine phosphorylation of HuR by JAK3 triggers dissociation and degradation of HuR target mRNAs
In response to stress conditions, many mammalian mRNAs accumulate in stress granules (SGs) together with numerous RNA-binding proteins that control mRNA turnover and translation. However, the signaling cascades that modulate the presence of ribonucleoprotein (RNP) complexes in SGs are poorly underst...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3902907/ https://ncbi.nlm.nih.gov/pubmed/24106086 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt903 |
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