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UneCLIPsing HuR nuclear function
The RNA-binding protein HuR, while known to stabilize cytoplasmic mRNAs, is largely nuclear. In this issue of Molecular Cell, Mukherjee et al. (2011) and Lebedeva et al. (2011) identify transcriptome-wide HuR-RNA interactions using PAR-CLIP, unveiling HuR’s nuclear role in pre-mRNA processing.
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3156671/ https://ncbi.nlm.nih.gov/pubmed/21816340 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.07.016 |
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