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miR-519 reduces cell proliferation by lowering RNA-binding protein HuR levels

Gene expression is potently regulated through the action of RNA-binding proteins (RBPs) and microRNAs (miRNAs). Here, we present evidence of a miRNA regulating an RBP. The RBP HuR can stabilize and modulate the translation of numerous target mRNAs involved in cell proliferation, but little is known...

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Detaylı Bibliyografya
Asıl Yazarlar: Abdelmohsen, Kotb, Srikantan, Subramanya, Kuwano, Yuki, Gorospe, Myriam
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2008
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2629338/
https://ncbi.nlm.nih.gov/pubmed/19088191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0809376106
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