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miR-519 suppresses tumor growth by reducing HuR levels

The RNA-binding protein HuR is highly abundant in many cancers. HuR expression was recently found to be repressed by microRNA miR-519, which potently lowered HuR translation without influencing HuR mRNA abundance. Here, we examined the levels of HuR and miR-519 in pairs of cancer and adjacent health...

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Détails bibliographiques
Auteurs principaux: Abdelmohsen, Kotb, Kim, Mihee M., Srikantan, Subramanya, Mercken, Evi M., Brennan, Sarah E., Wilson, Gerald M., de Cabo, Rafael, Gorospe, Myriam
Format: Artigo
Langue:Inglês
Publié: 2010
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057889/
https://ncbi.nlm.nih.gov/pubmed/20305372
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