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Competitive Regulation of Nucleolin Expression by HuR and miR-494

The RNA-binding protein (RBP) nucleolin promotes the expression of several proliferative proteins. Nucleolin levels are high in cancer cells, but the mechanisms that control nucleolin expression are unknown. Here, we show that nucleolin abundance is controlled posttranscriptionally via factors that...

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Detalhes bibliográficos
Main Authors: Tominaga, Kumiko, Srikantan, Subramanya, Lee, Eun Kyung, Subaran, Sarah S., Martindale, Jennifer L., Abdelmohsen, Kotb, Gorospe, Myriam
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3187287/
https://ncbi.nlm.nih.gov/pubmed/21859890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.05955-11
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