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miR-519 reduces cell proliferation by lowering RNA-binding protein HuR levels
Gene expression is potently regulated through the action of RNA-binding proteins (RBPs) and microRNAs (miRNAs). Here, we present evidence of a miRNA regulating an RBP. The RBP HuR can stabilize and modulate the translation of numerous target mRNAs involved in cell proliferation, but little is known...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2629338/ https://ncbi.nlm.nih.gov/pubmed/19088191 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0809376106 |
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