Loading...

The Conserved Salt Bridge in Human α-Defensin 5 Is Required for Its Precursor Processing and Proteolytic Stability

Mammalian α-defensins, expressed primarily in leukocytes and epithelia, play important roles in innate and adaptive immune responses to microbial infection. Six invariant cysteine residues forming three indispensable disulfide bonds and one Gly residue required structurally for an atypical β-bulge a...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Rajabi, Mohsen, de Leeuw, Erik, Pazgier, Marzena, Li, Jing, Lubkowski, Jacek, Lu, Wuyuan
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2490794/
https://ncbi.nlm.nih.gov/pubmed/18499668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801851200
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!