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Functional Determinants of Human Enteric α-Defensin HD5: CRUCIAL ROLE FOR HYDROPHOBICITY AT DIMER INTERFACE

Human α-defensins are cationic peptides that self-associate into dimers and higher-order oligomers. They bind protein toxins, such as anthrax lethal factor (LF), and kill bacteria, including Escherichia coli and Staphylococcus aureus, among other functions. There are six members of the human α-defen...

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Autors principals: Rajabi, Mohsen, Ericksen, Bryan, Wu, Xueji, de Leeuw, Erik, Zhao, Le, Pazgier, Marzena, Lu, Wuyuan
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3381126/
https://ncbi.nlm.nih.gov/pubmed/22573326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.367995
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