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Functional Determinants of Human Enteric α-Defensin HD5: CRUCIAL ROLE FOR HYDROPHOBICITY AT DIMER INTERFACE

Human α-defensins are cationic peptides that self-associate into dimers and higher-order oligomers. They bind protein toxins, such as anthrax lethal factor (LF), and kill bacteria, including Escherichia coli and Staphylococcus aureus, among other functions. There are six members of the human α-defen...

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Autores principales: Rajabi, Mohsen, Ericksen, Bryan, Wu, Xueji, de Leeuw, Erik, Zhao, Le, Pazgier, Marzena, Lu, Wuyuan
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3381126/
https://ncbi.nlm.nih.gov/pubmed/22573326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.367995
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