Molecular determinants for the interaction of human neutrophil α defensin 1 with its pro peptide

Human neutrophil α-defensins (HNPs) are cationic antimicrobial peptides that are synthesized in vivo as inactive precursors (proHNPs). Activation requires proteolytic excision of their anionic N-terminal inhibitory pro peptide. The pro peptide of proHNP1 also specifically interacts with and inhibits...

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Detaylı Bibliyografya
Asıl Yazarlar: Zou, Guozhang, de Leeuw, Erik, Lubkowski, Jacek, Lu, Wuyuan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2008
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754386/
https://ncbi.nlm.nih.gov/pubmed/18616948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.06.066
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