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Molecular determinants for the interaction of human neutrophil α defensin 1 with its pro peptide
Human neutrophil α-defensins (HNPs) are cationic antimicrobial peptides that are synthesized in vivo as inactive precursors (proHNPs). Activation requires proteolytic excision of their anionic N-terminal inhibitory pro peptide. The pro peptide of proHNP1 also specifically interacts with and inhibits...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2754386/ https://ncbi.nlm.nih.gov/pubmed/18616948 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.06.066 |
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