The WWOX Tumor Suppressor Is Essential for Postnatal Survival and Normal Bone Metabolism

The WW domain-containing oxidoreductase (WWOX) gene encodes a tumor suppressor. We have previously shown that targeted ablation of the Wwox gene in mouse increases the incidence of spontaneous and chemically induced tumors. To investigate WWOX function in vivo, we examined Wwox-deficient (Wwox(-)(/)...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Aqeilan, Rami I., Hassan, Mohammad Q., de Bruin, Alain, Hagan, John P., Volinia, Stefano, Palumbo, Titziana, Hussain, Sadiq, Lee, Suk-Hee, Gaur, Tripti, Stein, Gary S., Lian, Jane B., Croce, Carlo M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2008
Gaiak:
Molecular Basis of Cell and Developmental Biology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2490770/
https://ncbi.nlm.nih.gov/pubmed/18487609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800855200
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