Targeted deletion of Wwox reveals a tumor suppressor function

The WW domain-containing oxidoreductase (WWOX) spans the second most common fragile site of the human genome, FRA16D, located at 16q23, and its expression is altered in several types of human cancer. We have previously shown that restoration of WWOX expression in cancer cells suppresses tumorigenici...

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Detalhes bibliográficos
Principais autores: Aqeilan, Rami I., Trapasso, Francesco, Hussain, Sadiq, Costinean, Stefan, Marshall, Dean, Pekarsky, Yuri, Hagan, John P., Zanesi, Nicola, Kaou, Mohamed, Stein, Gary S., Lian, Jane B., Croce, Carlo M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1820689/
https://ncbi.nlm.nih.gov/pubmed/17360458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609783104
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