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Targeted deletion of Wwox reveals a tumor suppressor function
The WW domain-containing oxidoreductase (WWOX) spans the second most common fragile site of the human genome, FRA16D, located at 16q23, and its expression is altered in several types of human cancer. We have previously shown that restoration of WWOX expression in cancer cells suppresses tumorigenici...
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| Principais autores: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1820689/ https://ncbi.nlm.nih.gov/pubmed/17360458 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609783104 |
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