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A βα-barrel built by the combination of fragments from different folds

Combinatorial assembly of protein domains plays an important role in the evolution of proteins. There is also evidence that protein domains have come together from stable subdomains. This concept of modular assembly could be used to construct new well folded proteins from stable protein fragments. H...

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Autori principali: Bharat, Tanmay A. M., Eisenbeis, Simone, Zeth, Kornelius, Höcker, Birte
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2481348/
https://ncbi.nlm.nih.gov/pubmed/18632584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802202105
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