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Evolution, folding, and design of TIM barrels and related proteins

Proteins are chief actors in life that perform a myriad of exquisite functions. This diversity has been enabled through the evolution and diversification of protein folds. Analysis of sequences and structures strongly suggest that numerous protein pieces have been reused as building blocks and propa...

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Bibliographic Details
Published in:Curr Opin Struct Biol
Main Authors: Romero-Romero, Sergio, Kordes, Sina, Michel, Florian, Höcker, Birte
Format: Artigo
Language:Inglês
Published: Elsevier Science 2021
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8250049/
https://ncbi.nlm.nih.gov/pubmed/33453500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2020.12.007
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