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Extension of a de novo TIM barrel with a rationally designed secondary structure element
The ability to construct novel enzymes is a major aim in de novo protein design. A popular enzyme fold for design attempts is the TIM barrel. This fold is a common topology for enzymes and can harbor many diverse reactions. The recent de novo design of a four‐fold symmetric TIM barrel provides a wel...
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| Veröffentlicht in: | Protein Sci |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley & Sons, Inc.
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8040861/ https://ncbi.nlm.nih.gov/pubmed/33723882 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.4064 |
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