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A βα-barrel built by the combination of fragments from different folds

Combinatorial assembly of protein domains plays an important role in the evolution of proteins. There is also evidence that protein domains have come together from stable subdomains. This concept of modular assembly could be used to construct new well folded proteins from stable protein fragments. H...

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Bibliografske podrobnosti
Main Authors: Bharat, Tanmay A. M., Eisenbeis, Simone, Zeth, Kornelius, Höcker, Birte
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2481348/
https://ncbi.nlm.nih.gov/pubmed/18632584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802202105
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