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Structural and functional innovations in the real-time evolution of new (βα)(8) barrel enzymes
New genes can arise by duplication and divergence, but there is a fundamental gap in our understanding of the relationship between these genes, the evolving proteins they encode, and the fitness of the organism. Here we used crystallography, NMR dynamics, kinetics, and mass spectrometry to explain t...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5422803/ https://ncbi.nlm.nih.gov/pubmed/28416687 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1618552114 |
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