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A High Affinity Hepatocyte Growth Factor-binding Site in the Immunoglobulin-like Region of Met

Hepatocyte growth factor (HGF) and its high affinity receptor, the tyrosine kinase Met, play a key role in embryo development and tumor invasion. Both HGF and Met are established targets for cancer therapy. However, the mechanism of their interaction is complex and remains elusive. HGF is secreted a...

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Main Authors: Basilico, Cristina, Arnesano, Addolorata, Galluzzo, Maria, Comoglio, Paolo M., Michieli, Paolo
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2008
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2475716/
https://ncbi.nlm.nih.gov/pubmed/18495663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800727200
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