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Binding site on human immunoglobulin G for the affinity ligand HWRGWV

Affinity ligand HWRGWV has demonstrated the ability to isolate human immunoglobulin G (hIgG) from mammalian cell culture media. The ligand specifically binds hIgG through its Fc portion. This work shows that deglycosylation of hIgG has no influence on its binding to the HWRGWV ligand and the ligand...

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Bibliografiske detaljer
Main Authors: Yang, Haiou, Gurgel, Patrick V., Williams, D. Keith, Bobay, Benjamin G., Cavanagh, John, Muddiman, David C., Carbonell, Ruben G.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3906645/
https://ncbi.nlm.nih.gov/pubmed/20049844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jmr.967
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