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A High Affinity Hepatocyte Growth Factor-binding Site in the Immunoglobulin-like Region of Met

Hepatocyte growth factor (HGF) and its high affinity receptor, the tyrosine kinase Met, play a key role in embryo development and tumor invasion. Both HGF and Met are established targets for cancer therapy. However, the mechanism of their interaction is complex and remains elusive. HGF is secreted a...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Basilico, Cristina, Arnesano, Addolorata, Galluzzo, Maria, Comoglio, Paolo M., Michieli, Paolo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2475716/
https://ncbi.nlm.nih.gov/pubmed/18495663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800727200
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