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A High Affinity Hepatocyte Growth Factor-binding Site in the Immunoglobulin-like Region of Met
Hepatocyte growth factor (HGF) and its high affinity receptor, the tyrosine kinase Met, play a key role in embryo development and tumor invasion. Both HGF and Met are established targets for cancer therapy. However, the mechanism of their interaction is complex and remains elusive. HGF is secreted a...
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Hauptverfasser: | , , , , |
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Format: | Artigo |
Sprache: | Inglês |
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American Society for Biochemistry and Molecular Biology
2008
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2475716/ https://ncbi.nlm.nih.gov/pubmed/18495663 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800727200 |
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