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A High Affinity Hepatocyte Growth Factor-binding Site in the Immunoglobulin-like Region of Met

Hepatocyte growth factor (HGF) and its high affinity receptor, the tyrosine kinase Met, play a key role in embryo development and tumor invasion. Both HGF and Met are established targets for cancer therapy. However, the mechanism of their interaction is complex and remains elusive. HGF is secreted a...

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Bibliographische Detailangaben
Hauptverfasser: Basilico, Cristina, Arnesano, Addolorata, Galluzzo, Maria, Comoglio, Paolo M., Michieli, Paolo
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2475716/
https://ncbi.nlm.nih.gov/pubmed/18495663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800727200
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