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Amelioration of amyloid load by anti-Aβ single-chain antibody in Alzheimer mouse model
Parenteral immunization of transgenic mouse models of Alzheimer disease (AD) with synthetic amyloid β-peptide (Aβ) prevented or reduced Aβ deposits and attenuated their memory and learning deficits. A clinical trial of immunization with synthetic Aβ, however, was halted due to brain inflammation, pr...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2475574/ https://ncbi.nlm.nih.gov/pubmed/16630540 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2006.03.145 |
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