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Intracranial IL-17A overexpression decreases cerebral amyloid angiopathy by upregulation of ABCA1 in an animal model of Alzheimer’s disease

Neuroinflammation is a pervasive feature of Alzheimer’s disease (AD) and characterized by activated microglia, increased proinflammatory cytokines and/or infiltrating immune cells. T helper 17 (Th17) cells are found in AD brain parenchyma and interleukin-17A (IL-17A) is identified around deposits of...

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Detalhes bibliográficos
Publicado no:Brain Behav Immun
Main Authors: Yang, Junling, Kou, Jinghong, Lalonde, Robert, Fukuchi, Ken-ichiro
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5537015/
https://ncbi.nlm.nih.gov/pubmed/28526436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2017.05.012
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