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MyD88 Deficiency Ameliorates β-Amyloidosis in an Animal Model of Alzheimer's Disease

The accumulation of β-amyloid protein (Aβ) in the brain is thought to be a primary etiologic event in Alzheimer's disease (AD). Fibrillar Aβ plaques, a hallmark of AD abnormality, are closely associated with activated microglia. Activated microglia have contradictory roles in the pathogenesis o...

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書誌詳細
主要な著者: Lim, Jeong-Eun, Kou, Jinghong, Song, Min, Pattanayak, Abhinandan, Jin, Jingji, Lalonde, Robert, Fukuchi, Ken-ichiro
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Investigative Pathology 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157279/
https://ncbi.nlm.nih.gov/pubmed/21763676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.05.045
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