Positron Emission Tomography Imaging Using an Inverse Agonist Radioligand to Assess Cannabinoid CB(1) Receptors in Rodents

[(11)C]MePPEP is an inverse agonist and a radioligand developed to image cannabinoid CB(1) receptors with positron emission tomography (PET). It provides reversible, high specific signal in monkey brain. We assessed [(11)C]MePPEP in rodent brain with regard to receptor selectivity, susceptibility to...

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Main Authors: Terry, Garth, Liow, Jeih-San, Chernet, Eyassu, Zoghbi, Sami S., Phebus, Lee, Felder, Christian C., Tauscher, Johannes, Schaus, John M., Pike, Victor W., Halldin, Christer, Innis, Robert B.
Format: Artigo
Language:Inglês
Published: 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2474463/
https://ncbi.nlm.nih.gov/pubmed/18456516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroimage.2008.03.004
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