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Deadenylation is prerequisite for P-body formation and mRNA decay in mammalian cells
Deadenylation is the major step triggering mammalian mRNA decay. One consequence of deadenylation is the formation of nontranslatable messenger RNA (mRNA) protein complexes (messenger ribonucleoproteins [mRNPs]). Nontranslatable mRNPs may accumulate in P-bodies, which contain factors involved in tra...
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| Huvudupphovsmän: | , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
The Rockefeller University Press
2008
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2447901/ https://ncbi.nlm.nih.gov/pubmed/18625844 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200801196 |
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