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Human TOB, an Antiproliferative Transcription Factor, Is a Poly(A)-Binding Protein-Dependent Positive Regulator of Cytoplasmic mRNA Deadenylation

In mammalian cells, mRNA decay begins with deadenylation, which involves two consecutive phases mediated by the PAN2-PAN3 and the CCR4-CAF1 complexes, respectively. The regulation of the critical deadenylation step and its relationship with RNA-processing bodies (P-bodies), which are thought to be a...

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Detalhes bibliográficos
Main Authors: Ezzeddine, Nader, Chang, Tsung-Cheng, Zhu, Wenmiao, Yamashita, Akio, Chen, Chyi-Ying A., Zhong, Zhenping, Yamashita, Yukiko, Zheng, Dinghai, Shyu, Ann-Bin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2169145/
https://ncbi.nlm.nih.gov/pubmed/17785442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01254-07
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